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Peroxisome proliferator-activated receptors (PPARs) and mitochondria in relation to lifestyle-related diseases
(The University of Bergen, 2008-06-17)
Obesity is a growing life-style related health problem, and is often accompanied by dyslipidemia, insulin resistance and inflammation. This may in turn lead to hyperinsulinemia, increased risk of non-alcoholic fatty liver ...
Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress
(BioMed Central, 2011-10-25)
Background: Previous reports have shown an antiproliferative effect of the synthetic, 3-thia fatty acid tetradecylthioacetic acid (TTA) on different cancer cells in vitro and in vivo. The mechanisms behind the observed effects ...
Krill oil attenuates left ventricular dilatation after myocardial infarction in rats
(BioMed Central, 2011-12-29)
Background: In the western world, heart failure (HF) is one of the most important causes of cardiovascular mortality. Supplement with n-3 polyunsaturated fatty acids (PUFA) has been shown to improve cardiac function in HF ...