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Tetradecylthioacetic acid inhibits proliferation of human SW620 colon cancer cells - gene expression profiling implies endoplasmic reticulum stress

Lundemo, Anne G.; Pettersen, Caroline H.H.; Berge, Kjetil; Berge, Rolf Kristian; Schønberg, Svanhild A. (BioMed Central, 2011-10-25)

Background: Previous reports have shown an antiproliferative effect of the synthetic, 3-thia fatty acid tetradecylthioacetic acid (TTA) on different cancer cells in vitro and in vivo. The mechanisms behind the observed effects ...