Recent Submissions

  • Minimally invasive pancreatic surgery-where are we going? 

    Sahakyan, Mushegh; Labori, Knut Jørgen; Primavesi, Florian; Søreide, Kjetil; Stättner, Stefan; Edwin, Bjørn (Springer, 2019-03-13)
    Background Introduced in the mid-1990s, minimally invasive pancreatic surgery (MIPS) developed slowly over the next two decades, and its real-life benefits remained unclear. Methods In this review, the current status ...
    Journal article
  • Effects of a Cod Protein Hydrolysate Supplement on Symptoms, Gut Integrity Markers and Fecal Fermentation in Patients with Irritable Bowel Syndrome 

    Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Valeur, Jørgen; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (MDPI, 2019-07-17)
    Peptides from fish may beneficially affect several metabolic outcomes, including gut health and inflammation. The effect of fish peptides in subjects with irritable bowel syndrome (IBS) has not previously been investigated, ...
    Journal article
  • Huge variation in obtaining ethical permission for a non-interventional observational study in Europe 

    de Lange, Dylan W.; Guidet, Bertrand R.; Andersen, Finn Husøy; Artigas, Antonio; Bertolini, Guido; Moreno, Rui; Christensen, Steffen; Cecconi, Maurizio; Agvald-Öhman, Christina; Gradišek, Primož; Jung, Christian; Marsh, Brian J.; Oeyen, Sandra; Bollen Pinto, Bernardo; Szczeklik, Wojciech; Watson, Ximena; Zafeiridis, Tilemachos; Flaatten, Hans (BMC, 2019-06-03)
    Background Ethical approval (EA) must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Methods Sixteen European ...
    Journal article
  • Overweight and eating disorders in people with epilepsy 

    Kolstad, Eivind (The University of Bergen, 2019-09-27)
    Background: Epilepsy is a common neurological disease and occurs in 0.7-1.3 % of the general population. It is associated with comorbid mental disorders such as depression and anxiety, and with a high risk for adverse ...
    Doctoral thesis
  • Risk factors for revision after anterior cruciate ligament reconstruction 

    Persson, Andreas (The University of Bergen, 2019-09-06)
    The overall aim of this thesis was to investigate risk factors for revision anterior cruciate ligament (ACL) reconstruction with a special attention to surgical technique (graft choice and choice of graft fixation) and ...
    Doctoral thesis
  • Outcome of 881 total hip arthroplasties in 747 patients 21 years or younger: data from the Nordic Arthroplasty Register Association (NARA) 1995-2016 

    Halvorsen, Vera Baasland; Fenstad, Anne Marie; Engesæter, Lars B.; Nordsletten, Lars; Overgaard, Søren; Pedersen, Alma B.; Kärrholm, Johan; MOHADDES, MAZIAR; Eskelinen, Antti; Mäkelä, Keijo T.; Röhrl, Stephan Maximillian (Taylor & Francis, 2019-05-19)
    Background and purpose — The literature is scarce on the outcome of the youngest patients with total hip arthroplasties (THAs). We analyzed register data, revision risk, and related factors in patients 21 years or younger ...
    Journal article
  • New methods clear the dust off old biopsies. RNA sequencing of FFPE kidney biopsies 

    Eikrem, Øystein Solberg (The University of Bergen, 2019-06-07)
    Background and aims: Formalin-fixed, paraffin-embedded (FFPE) tissues are an underused resource for molecular analyses. We wanted to exploit renal biopsies also on the mRNA level to elucidate pathophysiological mechanisms ...
    Doctoral thesis
  • Hospital readmission after ischemic stroke or TIA 

    Bjerkreim, Anna Therese (The University of Bergen, 2019-09-06)
    Background: Considerable advances in the field of stroke medicine have led to declining trends in stroke incidence, disability, and mortality in the Western world. Despite this, the absolute number of people affected ...
    Doctoral thesis
  • One-year versus five-year hospital readmission after ischemic stroke and TIA 

    Bjerkreim, Anna Therese; Næss, Halvor; Khanevski, Andrej; Thomassen, Lars; Waje-Andreassen, Ulrike; Logallo, Nicola (BioMed Central, 2019-01-29)
    Background: The burden of hospital readmission after stroke is substantial, but little knowledge exists on factors associated with long-term readmission after stroke. In a cohort comprising patients with ischemic stroke ...
    Journal article
  • The impact of ischaemic stroke subtype on 30-day hospital readmissions 

    Bjerkreim, Anna Therese; Khanevski, Andrej; Selvik, Henriette Aurora; Waje-Andreassen, Ulrike; Thomassen, Lars; Næss, Halvor; Logallo, Nicola (Hindawi, 2018-12-03)
    Background. Stroke aetiologymay affect the risk and causes of readmission after ischaemic stroke (IS) and transient ischaemic attack (TIA) due to differences in risk factors, functional outcome, and treatment.We aimed to ...
    Journal article
  • Decompression alone versusdecompression with instrumental fusionthe NORDSTEN degenerativespondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial 

    Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Lønne, Greger; Indrekvam, Kari; Aaen, Jørn; Grundnes, Oliver; Hellum, Christian (BioMed Central, 2019-01-05)
    Background: Fusion in addition to decompression has become the standard treatment for lumbar spinal stenosis with degenerative spondylolisthesis (DS). The evidence for performing fusion among these patients is conflicting ...
    Journal article
  • Clinical outcome after surgery for lumbarspinal stenosis in patients with insignificantlower extremity pain. A prospective cohortstudy from the Norwegian registry for spine surgery 

    Hermansen, Erland; Myklebust, Tor Åge; Austevoll, Ivar Magne; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Grundnes, Oliver; Aaen, Jørn Ståle; Brox, Jens Ivar; Hellum, Christian; Indrekvam, Kari (BMC, 2019-01-22)
    Background: Spinal stenosis is a clinical diagnosis in which the main symptom is pain radiating to the lower extremities, or neurogenic claudication. Radiological spinal stenosis is commonly observed in the population and ...
    Journal article
  • Helicopter-based Emergency Medical Service: dispatches, decisions and patient outcome 

    Østerås, Øyvind (The University of Bergen, 2019-09-12)
    Introduction: Although Norway has one of the most developed air ambulance services in the world, its helicopter emergency medical service (HEMS) capacity is limited. Few studies have assessed the medical decisions involved ...
    Doctoral thesis
  • Barriers and Facilitators for Implementing a Decision Support System to Prevent and Treat Disease-Related Malnutrition in a Hospital Setting: Qualitative Study 

    Paulsen, Mari Mohn; Varsi, Cecilie; Paur, Ingvild; Tangvik, Randi Julie; Andersen, Lene Frost (JMIR Publications, 2019-04-26)
    Background: Disease-related malnutrition is a challenge among hospitalized patients. Despite guidelines and recommendations for prevention and treatment, the condition continues to be prevalent. The MyFood system is a ...
    Journal article
  • Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics 

    Beaumont, Robin N.; Warrington, Nicole M.; Cavadino, Alana; Tyrrell, Jessica; Nodzenski, Michael; Horikoshi, Momoko; Geller, Frank; Myhre, Ronny; Richmond, Rebecca C.; Paternoster, Lavinia; Bradfield, Jonathan P.; Kreiner-Møller, Eskil; Huikari, Ville; Metrustry, Sarah; Lunetta, Kathryn L.; Painter, Jodie N.; Hottenga, Jouke-Jan; Allard, Catherine; Barton, Sheila J.; Espinosa, Ana; Marsh, Julie A.; Potter, Catherine; Zhang, Ge; Ang, Wei; Berry, Diane J.; Bouchard, Luigi; Das, Shikta; Hakonarson, Hakon; Heikkinen, Jani; Helgeland, Øyvind; Hocher, Berthold; Hofman, Albert; Inskip, Hazel M.; Jones, Samuel E.; Kogevinas, Manolis; Lind, Penelope A.; Marullo, Letizia; Medland, Sarah E.; Murray, Anna; Murray, Jeffrey C.; Njølstad, Pål Rasmus; Nohr, Ellen A.; Reichetzeder, Christoph; Ring, Susan M.; Ruth, Katherine S.; Santa-Marina, Loreto; Scholtens, Denise M.; Sebert, Sylvain; Sengpiel, Verena; Tuke, Marcus A.; Vaudel, Marc; Weedon, Michael N.; Willemsen, Gonneke; Wood, Andrew R.; Yaghootkar, Hanieh; Muglia, Louis J.; Bartels, Meike; Relton, Caroline L.; Pennell, Craig E.; Chatzi, Leda; Estivill, Xavier; Holloway, John W.; Boomsma, Dorret I.; Montgomery, Grant W.; Murabito, Joanne M.; Spector, Tim D.; Power, Christine; Järvelin, Marjo-Riitta; Bisgaard, Hans; Grant, Struan F.A.; Sørensen, Thorkild I.A.; Jaddoe, Vincent W.; Jacobsson, Bo; Melbye, Mads; McCarthy, Mark I.; Hattersley, Andrew T.; Hayes, M. Geoffrey; Hivert, Marie-France; Frayling, Timothy M.; Felix, Janine F.; Hyppönen, Elina; Lowe, William L.; Evans, David M.; Lawlor, Debbie A.; Feenstra, Bjarke; Freathy, Rachel M. (Oxford University Press, 2018-02)
    Genome-wide association studies of birth weight have focused on fetal genetics, whereas relatively little is known about the role of maternal genetic variation. We aimed to identify maternal genetic variants associated ...
    Journal article
  • Tear production levels and dry eye disease severity in a large Norwegian cohort 

    Yazdani, Mazyar; Chen, Xiangjun; Tashbayev, Behzod; Utheim, Øygunn Aass; Ræder, Sten; Lagli, Neil; Stojanovic, Aleksandar; Dartt, Darlene Ann; Utheim, Tor Paaske (Taylor & Francis, 2018)
    Purpose: To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear ...
    Journal article
  • Global inequities in precision medicine and molecular cancer research 

    Drake, Thomas M.; Knight, Stephen R.; Harrison, Ewen M.; Søreide, Kjetil (Frontiers, 2018-09-04)
    Precision medicine based upon molecular testing is heralded as a revolution in how cancer is prevented, diagnosed, and treated. Large efforts across the world aim to conduct comprehensive molecular profiling of disease to ...
    Journal article
  • High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets 

    Reppe, Sjur; Jackson, Catherine; Ringstad, Håkon; Tønseth, Kim Alexander; Bakke, Hege Gilbø; Eidet, Jon Roger; Utheim, Tor Paaske (Hindawi, 2018-11-18)
    There is a need to optimize storage conditions to preserve cell characteristics during transport of cultured cell sheets from specialized culture units to distant hospitals. In this study, we aimed to explore a method to ...
    Journal article
  • Efficacy of different types of cognitive enhancers for patients with schizophrenia: a meta-analysis 

    Sinkeviciute, Igne; Begemann, Marieke; Prikken, Merel; Oranje, Bob; Johnsen, Erik; Lei, Wan U.; Hugdahl, Kenneth; Kroken, Rune Andreas; Rau, Carina; Jacobs, Jolien D.; Mattaroccia, Silvia; Sommer, Iris Else Clara (Springer Nature, 2018)
    Cognitive impairment is a core feature of schizophrenia, which is predictive for functional outcomes and is, therefore, a treatment target in itself. Yet, literature on efficacy of different pharmaco-therapeutic options ...
    Journal article

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