Recent Submissions

  • Advanced imaging biomarkers in endometrial cancer 

    Ytre-Hauge, Sigmund (The University of Bergen, 2019-12-11)
    Background: Endometrial cancer is the most common gynecological cancer in highdeveloped regions of the world, and the incidence has been increasing over the last half century, largely driven by a concurrent increase in ...
    Doctoral thesis
  • Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells 

    Utheim, Øygunn Aass; Pasovic, Lara; Ræder, Sten; Eidet, Jon Roger; Fostad, Ida; Sehic, Amer; Roald, Borghild; de la Paz, Maria Fideliz; Lyberg, Torstein; Dartt, Darlene A.; Utheim, Tor Paaske (PLOS, 2019)
    Purpose Transplantation of limbal stem cells is a promising therapy for limbal stem cell deficiency. Limbal cells can be harvested from either a healthy part of the patient’s eye or the eye of a donor. Small explants are ...
    Journal article
  • Gene expression profiles of CMS2-epithelial/canonical colorectal cancers are largely driven by DNA copy number gains 

    Berg, Kaja Christine Graue; Sveen, Anita; Høland, Maren; Alagaratnam, Sharmini; Rasmussen, Marianne Berg; Danielsen, Stine Aske; Nesbakken, Arild; Søreide, Kjetil; Lothe, Ragnhild A (Springer Nature, 2019-07-15)
    About 80% of colorectal cancers (CRCs) have chromosomal instability, which is an integral part of aggressive malignancy development, but the importance of specific copy number aberrations (CNAs) in modulating gene expression, ...
    Journal article
  • GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study 

    Rongve, Arvid; Witoelar, Aree; Ruiz, Agustín; Athanasiu, Lavinia; Abdelnour, Carla; Clarimon, Jordi; Heilmann-Heimbach, Stefanie; Hernández, Isabel; Moreno-Grau, Sonia; de Rojas, Itziar; Morenas-Rodríguez, Estrella; Fladby, Tormod; Sando, Sigrid Botne; Bråthen, Geir; Blanc, Frédéric; Bousiges, Olivier; Lemstra, Afina W.; van Steenoven, Inger; Londos, Elisabet; Almdahl, Ina Selseth; Pålhaugen, Lene; Eriksen, Jon Alm; Djurovic, Srdjan; Stordal, Eystein; Saltvedt, Ingvild; Ulstein, Ingun; Bettella, Francesco; Desikan, Rahul S.; Idland, Ane-Victoria; Toft, Mathias; Pihlstrøm, Lasse; Snaedal, Jon; Tárraga, Lluís; Boada, Mercè; Lleó, Alberto; Stefánsson, Hreinn; Stefánsson, Kári; Ramírez, Alfredo; Aarsland, Dag; Andreassen, Ole Andreas (Nature Research, 2019-05-07)
    Dementia with Lewy Bodies (DLB) is a common neurodegenerative disorder with poor prognosis and mainly unknown pathophysiology. Heritability estimates exceed 30% but few genetic risk variants have been identified. Here we ...
    Journal article
  • Fine needle aspirates of kidneys: A promising tool for RNA sequencing in native and transplanted kidneys 

    Eikrem, Øystein Solberg; Walther, Tedd Christian; Flatberg, Arnar; Beisvag, Vidar; Strauss, Philipp; Farstad, Magnus; Beisland, Christian; Koch, Even; Mueller, Thomas F.; Marti, Hans-Peter (BMC, 2018-09-18)
    Background: Transcriptome analysis is emerging as emerging as a promising tool to enhance precision of diagnosis and monitoring in solid organ transplantation. Clinical progress has however been hampered by the current ...
    Journal article
  • Terminal digit preference: a source of measurement error in breast cancer diameter reporting 

    Tsuruda, Kaitlyn; Hofvind, Solveig; Akslen, Lars A.; Hoff, Solveig Roth; Veierød, Marit Bragelien (Taylor & Francis, 2019)
    Objectives: Women diagnosed with breast cancer are offered treatment and therapy based on tumor characteristics, including tumor diameter. There is scarce knowledge whether tumor diameter is accurately reported, or whether ...
    Journal article
  • Minimally invasive pancreatic surgery-where are we going? 

    Sahakyan, Mushegh; Labori, Knut Jørgen; Primavesi, Florian; Søreide, Kjetil; Stättner, Stefan; Edwin, Bjørn (Springer, 2019-03-13)
    Background Introduced in the mid-1990s, minimally invasive pancreatic surgery (MIPS) developed slowly over the next two decades, and its real-life benefits remained unclear. Methods In this review, the current status ...
    Journal article
  • Effects of a Cod Protein Hydrolysate Supplement on Symptoms, Gut Integrity Markers and Fecal Fermentation in Patients with Irritable Bowel Syndrome 

    Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Valeur, Jørgen; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (MDPI, 2019-07-17)
    Peptides from fish may beneficially affect several metabolic outcomes, including gut health and inflammation. The effect of fish peptides in subjects with irritable bowel syndrome (IBS) has not previously been investigated, ...
    Journal article
  • Huge variation in obtaining ethical permission for a non-interventional observational study in Europe 

    de Lange, Dylan W.; Guidet, Bertrand R.; Andersen, Finn Husøy; Artigas, Antonio; Bertolini, Guido; Moreno, Rui; Christensen, Steffen; Cecconi, Maurizio; Agvald-Öhman, Christina; Gradišek, Primož; Jung, Christian; Marsh, Brian J.; Oeyen, Sandra; Bollen Pinto, Bernardo; Szczeklik, Wojciech; Watson, Ximena; Zafeiridis, Tilemachos; Flaatten, Hans (BMC, 2019-06-03)
    Background Ethical approval (EA) must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Methods Sixteen European ...
    Journal article
  • Biomarker and pathology studies in neurodegenerative cognitive impairment 

    Skogseth, Ragnhild Eide (The University of Bergen, 2019-10-16)
    Background: Dementia is a major cause of functional impairment and early death in older age groups. Neurodegenerative disorders are the most common cause of dementia. The most frequent neuropathological lesions include ...
    Doctoral thesis
  • Overweight and eating disorders in people with epilepsy 

    Kolstad, Eivind (The University of Bergen, 2019-09-27)
    Background: Epilepsy is a common neurological disease and occurs in 0.7-1.3 % of the general population. It is associated with comorbid mental disorders such as depression and anxiety, and with a high risk for adverse ...
    Doctoral thesis
  • Risk factors for revision after anterior cruciate ligament reconstruction 

    Persson, Andreas (The University of Bergen, 2019-09-06)
    The overall aim of this thesis was to investigate risk factors for revision anterior cruciate ligament (ACL) reconstruction with a special attention to surgical technique (graft choice and choice of graft fixation) and ...
    Doctoral thesis
  • Outcome of 881 total hip arthroplasties in 747 patients 21 years or younger: data from the Nordic Arthroplasty Register Association (NARA) 1995-2016 

    Halvorsen, Vera Baasland; Fenstad, Anne Marie; Engesæter, Lars B.; Nordsletten, Lars; Overgaard, Søren; Pedersen, Alma B.; Kärrholm, Johan; MOHADDES, MAZIAR; Eskelinen, Antti; Mäkelä, Keijo T.; Röhrl, Stephan Maximillian (Taylor & Francis, 2019-05-19)
    Background and purpose — The literature is scarce on the outcome of the youngest patients with total hip arthroplasties (THAs). We analyzed register data, revision risk, and related factors in patients 21 years or younger ...
    Journal article
  • New methods clear the dust off old biopsies. RNA sequencing of FFPE kidney biopsies 

    Eikrem, Øystein Solberg (The University of Bergen, 2019-06-07)
    Background and aims: Formalin-fixed, paraffin-embedded (FFPE) tissues are an underused resource for molecular analyses. We wanted to exploit renal biopsies also on the mRNA level to elucidate pathophysiological mechanisms ...
    Doctoral thesis
  • Hospital readmission after ischemic stroke or TIA 

    Bjerkreim, Anna Therese (The University of Bergen, 2019-09-06)
    Background: Considerable advances in the field of stroke medicine have led to declining trends in stroke incidence, disability, and mortality in the Western world. Despite this, the absolute number of people affected ...
    Doctoral thesis
  • One-year versus five-year hospital readmission after ischemic stroke and TIA 

    Bjerkreim, Anna Therese; Næss, Halvor; Khanevski, Andrej; Thomassen, Lars; Waje-Andreassen, Ulrike; Logallo, Nicola (BioMed Central, 2019-01-29)
    Background: The burden of hospital readmission after stroke is substantial, but little knowledge exists on factors associated with long-term readmission after stroke. In a cohort comprising patients with ischemic stroke ...
    Journal article
  • The impact of ischaemic stroke subtype on 30-day hospital readmissions 

    Bjerkreim, Anna Therese; Khanevski, Andrej; Selvik, Henriette Aurora; Waje-Andreassen, Ulrike; Thomassen, Lars; Næss, Halvor; Logallo, Nicola (Hindawi, 2018-12-03)
    Background. Stroke aetiologymay affect the risk and causes of readmission after ischaemic stroke (IS) and transient ischaemic attack (TIA) due to differences in risk factors, functional outcome, and treatment.We aimed to ...
    Journal article
  • Decompression alone versusdecompression with instrumental fusionthe NORDSTEN degenerativespondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial 

    Austevoll, Ivar Magne; Hermansen, Erland; Fagerland, Morten; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Brox, Jens Ivar; Lønne, Greger; Indrekvam, Kari; Aaen, Jørn; Grundnes, Oliver; Hellum, Christian (BioMed Central, 2019-01-05)
    Background: Fusion in addition to decompression has become the standard treatment for lumbar spinal stenosis with degenerative spondylolisthesis (DS). The evidence for performing fusion among these patients is conflicting ...
    Journal article
  • Clinical outcome after surgery for lumbarspinal stenosis in patients with insignificantlower extremity pain. A prospective cohortstudy from the Norwegian registry for spine surgery 

    Hermansen, Erland; Myklebust, Tor Åge; Austevoll, Ivar Magne; Rekeland, Frode; Solberg, Tore; Storheim, Kjersti; Grundnes, Oliver; Aaen, Jørn Ståle; Brox, Jens Ivar; Hellum, Christian; Indrekvam, Kari (BMC, 2019-01-22)
    Background: Spinal stenosis is a clinical diagnosis in which the main symptom is pain radiating to the lower extremities, or neurogenic claudication. Radiological spinal stenosis is commonly observed in the population and ...
    Journal article
  • Helicopter-based Emergency Medical Service: dispatches, decisions and patient outcome 

    Østerås, Øyvind (The University of Bergen, 2019-09-12)
    Introduction: Although Norway has one of the most developed air ambulance services in the world, its helicopter emergency medical service (HEMS) capacity is limited. Few studies have assessed the medical decisions involved ...
    Doctoral thesis

View more