Recent Submissions

  • Cervical cancer screening among immigrants in Norway : Challenges, possibilities and the effect of an intervention 

    Møen, Kathy Ainul (The University of Bergen, 2019-11-28)
    The aims of this thesis were: (i) to determine immigrants’ participation rate to CCS compared to non-immigrants and predictors to take the CCS-test, (ii) to obtain knowledge of HCPs perceptions regarding CCS test among ...
    Doctoral thesis
  • Discovery of shared genomic loci using the conditional false discovery rate approach 

    Smeland, Olav Bjerkehagen; Frei, Oleksandr; Shadrin, Alexey A.; O'Connell, Kevin; Fan, Chun Chieh; Bahrami, Shahram; Holland, Dominic; Djurovic, Srdjan; Thompson, Wesley Kurt; Dale, Anders; Andreassen, Ole Andreas (Springer Berlin Heidelberg, 2019-09-13)
    In recent years, genome-wide association study (GWAS) sample sizes have become larger, the statistical power has improved and thousands of trait-associated variants have been uncovered, offering new insights into the genetic ...
    Journal article
  • Creatinine, total cysteine and uric acid are associated with serum retinol in patients with cardiovascular disease 

    Olsen, Thomas; Vinknes, Kathrine; Blomhoff, Rune; Lysne, Vegard; Midttun, Øivind; Dhar, Indu; Ueland, Per Magne; Svingen, Gard Frodahl Tveitevåg; Pedersen, Eva Ringdal; Drevon, Christian A; Refsum, Helga; Nygård, Ottar (Springer Berlin Heidelberg, 2019-09-09)
    Purpose: We hypothesized that biomarkers and dietary factors related to cardiovascular disease risk were associated with serum retinol and evaluated these potential associations in patients with suspected coronary artery ...
    Journal article
  • Circulating high sensitivity C reactive protein concentrations and risk of lung cancer : Nested case-control study within Lung Cancer Cohort Consortium 

    Muller, David C.; Larose, Tricia L; Hodge, Allison; Guida, Florence; Langhammer, Arnulf; Grankvist, Kjell; Meyer, Klaus; Cai, Qiuyin; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Albanes, Demetrius; Giles, Graham G.; Sesso, Howard D.; Lee, I-Min; Gaziano, J. Michael; Yuan, Jian-Min; Hoffman Bolton, Judith; Buring, Julie E.; Visvanathan, Kala; Le Marchand, Loic; Purdue, Mark P.; Caporaso, Neil E.; Midttun, Øivind; Ueland, Per Magne; Prentice, Ross L.; Weinstein, Stephanie J.; Stevens, Victoria L.; Zheng, Wei; Blot, William J.; Shu, Xiao-Ou; Zhang, Xuehong; Xiang, Yong-Bing; Koh, Woon-Puay; Hveem, Kristian; Thomson, Cynthia A.; Pettinger, Mary; Engström, Gunnar; Brunnström, Hans; Milne, Roger L.; Stampfer, Meir J.; Han, Jiali; Johansson, Mikael; Brennan, Paul; Severi, Gianluca; Johansson, Mattias (BMJ Publishing Group, 2019-01-03)
    Objectives: Inflammation may play an important role in lung cancer pathogenesis. Previous studies have suggested an association between C-reactive protein (CRP) as a marker of inflammation, and risk of lung cancer, but ...
    Journal article
  • The PI3K-Akt-mTOR intracellular signaling pathway in human acute myeloid leukemia 

    Nepstad, Ina (The University of Bergen, 2019-03-08)
    Acute myeloid leukemia (AML) is a heterogeneous malignancy where disruption of normal intracellular signaling occurs due to mutations or abnormal external signaling. Many pathways have emerged as potential targets for ...
    Doctoral thesis
  • Evaluation of treatment response in extrapulmonary tuberculosis in a low-resource setting 

    Jørstad, Melissa Davidsen; Dyrhol-Riise, Anne Ma; Aßmus, Jörg; Marijani, Msafiri; Sviland, Lisbeth; Mustafa, Tehmina (BMC, 2019-05-16)
    Background Diagnosing extrapulmonary tuberculosis (EPTB) is challenging and many patients are initiated on empirical anti-TB treatment without a laboratory confirmed diagnosis. Monitoring treatment response is thus important ...
    Journal article
  • Skeletal effects of the saturated 3-thia fatty acid tetradecylthioacetic acid in rats 

    Stunes, Astrid Kamilla; Westbroek, Irene; Fossmark, Reidar; Berge, Rolf Kristian; Reseland, Janne Elin; Syversen, Unni (Hindawi Publishing, 2011-09-06)
    This study explores the skeletal effects of the peroxisome proliferator activated receptor (PPAR)pan agonist tetradecylthioacetic acid (TTA). Rats, without (Study I) and with ovariectomy (OVX) or sham operation (Study II), ...
    Journal article
  • Variation in staff perceptions of patient safety climate across work sites in Norwegian general practitioner practices and out-of-hour clinics 

    Deilkås, Ellen C Tveter; Hofoss, Dag; Hansen, Elisabeth Holm; Bondevik, Gunnar Tschudi (PLOS Public Library of Science, 2019-04-10)
    Introduction Measuring staff perceptions with safety climate surveys is a promising approach to addressing patient safety. Variation in safety climate scores between work sites may predict variability in risk related ...
    Journal article
  • Severe traumatic brain injury in Norway: Impact of age on outcome 

    Røe, Cecilie; Skandsen, Toril; Anke, Audny; Ader, Tiina; Vik, Anne; Lund, Stine Borgen; Manskow, Unn Sollid; Sollid, Snorre; Sundstrøm, Terje; Hestnes, Morten; Andelic, Nada (Foundation of Rehabilitation Information, 2013-04-23)
    Objective: The aim of this study was to investigate the influence of age on mortality and 3-month outcome in a Norwegian cohort of patients with severe traumatic brain injury (TBI). Methods: Norwegian residents ≥ 16 ...
    Journal article
  • Minimally invasive pancreatic surgery-where are we going? 

    Sahakyan, Mushegh; Labori, Knut Jørgen; Primavesi, Florian; Søreide, Kjetil; Stättner, Stefan; Edwin, Bjørn (Springer, 2019-03-13)
    Background Introduced in the mid-1990s, minimally invasive pancreatic surgery (MIPS) developed slowly over the next two decades, and its real-life benefits remained unclear. Methods In this review, the current status ...
    Journal article
  • General practitioners’ and out-of-hours doctors’ role as gatekeeper in emergency admissions to somatic hospitals in Norway: registry-based observational study 

    Blinkenberg, Jesper; Pahlavanyali, Sahar; Hetlevik, Øystein; Sandvik, Hogne; Hunskaar, Steinar (BMC, 2019-08-14)
    Background Primary care doctors have a gatekeeper function in many healthcare systems, and strategies to reduce emergency hospital admissions often focus on general practitioners’ (GPs’) and out-of-hours (OOH) doctors’ ...
    Journal article
  • Burden and characteristics of the comorbidity tuberculosis - diabetes in Europe : TBnet prevalence survey and case-control study 

    Sane Schepisi, Monica; Navarra, Assunta; Altet Gómez, Maria de las Nieves; Dudnyk, Andrii; Dyrhol-Riise, Anne Ma; Esteban, Jaime; Giorgetti, Pier Francesco; Gualano, Gina; Guglielmetti, Lorenzo; Heyckendorf, Jan; Kaluzhenina, Anna; Lange, Berit; Lange, Christoph; Manika, Katerina; Miah, Jalal; Nanovic, Zorica; Pontali, Emanuele; Prego, Monica Rios; Solovič, Ivan; Tiberi, Simon; Palmieri, Fabrizio; Girardi, Enrico (Oxford University Press, 2019-01)
    Background: The growing burden of diabetes mellitus (DM) is posing a threat to global tuberculosis (TB) control. DM triples the risk of developing TB, modifies the presenting features of pulmonary TB, and worsens TB treatment ...
    Journal article
  • Associations between home deaths and end-of-life nursing care trajectories for community-dwelling people: a population-based registry study 

    Kjellstadli, Camilla; Han, Ling; Allore, Heather G; Flo, Elisabeth; Husebø, Bettina; Hunskaar, Steinar (BMC, 2019-10-15)
    Background: Few studies have estimated planned home deaths compared to actual place of death in a general population or the longitudinal course of home nursing services and associations with place of death. We aimed to ...
    Journal article
  • Anatomy and evolution of database search engines — a central component of mass spectrometry based proteomic workflows 

    Verheggen, Kenneth; Ræder, Helge; Berven, Frode; Martens, Lennart Martens; Barsnes, Harald; Vaudel, Marc (Wiley, 2017-09-13)
    Sequence database search engines are bioinformatics algorithms that identify peptides from tandem mass spectra using a reference protein sequence database. Two decades of development, notably driven by advances in mass ...
    Journal article
  • Reliabilitet av den norske versjonen av PainDETECT: en test-retest studie 

    Myhre, Anette Govenius Melsom (The University of Bergen, 2019-11-14)
    Bakgrunn: PainDETECT Questionnaire (PD-Q) er et spørreskjema som pasienten kan fylle ut på egenhånd med mål om å avdekke neuropatisk smerte. Skjemaet er oversatt til 38 språk, og har vist god reliabilitet og validitet. ...
    Master thesis
  • The Role of Axl in Cancer and Stem Cell Plasticity: in vivo Lineage Tracing and Imaging Mass Cytometry Analysis 

    Rayford, Austin James (The University of Bergen, 2019-11-14)
    Master thesis
  • Low temperature and low UV indexes correlated with peaks of influenza virus activity in Northern Europe during 2010-2018 

    Ianevski, Aleksandr; Zusinaite, Eva; Shtaida, Nastassia; Kallio-Kokko, Hannimari; Valkonen, Mia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Dumpis, Uga; Vitkauskiene, Astra; Stašaitis, Kestutis; Öhrmalm, Christina; Bondeson, Kåre; Bergqvist, Anders; Cox, Rebecca Jane; Tenson, Tanel; Merits, Andres; Kainov, Denis (MDPI, 2019-03-01)
    With the increasing pace of global warming, it is important to understand the role of meteorological factors in influenza virus (IV) epidemics. In this study, we investigated the impact of temperature, UV index, humidity, ...
    Journal article
  • Effects of a Cod Protein Hydrolysate Supplement on Symptoms, Gut Integrity Markers and Fecal Fermentation in Patients with Irritable Bowel Syndrome 

    Dale, Hanna Fjeldheim; Jensen, Caroline; Hausken, Trygve; Valeur, Jørgen; Hoff, Dag Arne Lihaug; Lied, Gülen Arslan (MDPI, 2019-07-17)
    Peptides from fish may beneficially affect several metabolic outcomes, including gut health and inflammation. The effect of fish peptides in subjects with irritable bowel syndrome (IBS) has not previously been investigated, ...
    Journal article
  • PCR based Malaria diagnostics : – Method development and application 

    Haanshuus, Christel Gill (The University of Bergen, 2019-11-12)
    Background Almost half of the world’s population is at risk of malaria. Malaria is a parasitic vector borne disease spread by infected female Anopheles mosquitos. The protozoan parasite belongs to the genus Plasmodium ...
    Doctoral thesis
  • Huge variation in obtaining ethical permission for a non-interventional observational study in Europe 

    de Lange, Dylan W.; Guidet, Bertrand R.; Andersen, Finn Husøy; Artigas, Antonio; Bertolini, Guido; Moreno, Rui; Christensen, Steffen; Cecconi, Maurizio; Agvald-Öhman, Christina; Gradišek, Primož; Jung, Christian; Marsh, Brian J.; Oeyen, Sandra; Bollen Pinto, Bernardo; Szczeklik, Wojciech; Watson, Ximena; Zafeiridis, Tilemachos; Flaatten, Hans (BMC, 2019-06-03)
    Background Ethical approval (EA) must be obtained before medical research can start. We describe the differences in EA for an pseudonymous, non-interventional, observational European study. Methods Sixteen European ...
    Journal article

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